![]() Topological overlap (wTO), that explicitly addresses the sign of wTO values. Results: Here, we present an R package for calculating the weighted ![]() Typically, suchĪnalyses are focused on the comparison of networks or data from two differentĬonditions. Multiple networks to identify deferentially changed links. However, since some genes are able to up- orĭown-regulate other genes, it is important to explicitly consider both positiveĪnd negative correlations when constructing a gene co-expression network.Īdditionally, there has been a growing interest in the systematic comparison of Packages exist for generating and analyzing such networks, either fromĬorrelation scores or the absolute value of a transformed score called weighted Background: Gene co-expression network analyses have become a centralĪpproach for the systems-level analysis of biological data. ![]()
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January 2023
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